We explain what chromosomes are and how their structure is composed. In addition, its main functions and types of chromosomes.
What are chromosomes
Chromosomes are the highly organized structures inside biological cells, made up of DNA and other protein, and where most of the Genetic information of an individual. They have a definite shape of X, which is perfectly observable during the stages of cell division or replication (meiosis or mitosis).
Each chromosome has a characteristic shape and size, and they are found in pairs, usually in identical numbers for all individuals of the same species. Depending on the number of chromosomes they have (chromosome load), the cells it can be diploid (2n) or haploid (1n). The chromosome number of the human species is 46 pairs.
Chromosomes were discovered in vegetables cells at the end of the 19th century by the scientists Karl Wilhelm von Nägeli (Switzerland) and Edouard Van Benenden (Belgium), independently, and their name comes precisely from the tinctures used to be able to observe them (from the Greek:chroma, "Color", andsoma, "Body").
But it was not until the 20th century that the role of chromosomes in heredity and genetic transmission was understood: we had to wait for Mendel's laws and the first research about him DNA.
In the cells of eukaryotic beings (that is, provided with cell nucleus), chromosomes are made up of chromatin, the substance that makes up DNA, RNA and other proteins, some basic called histones and some non-histones. All this makes up nucleosomes, forming inactive groups of DNA that make up the chromosomes themselves.
Chromosome structure
Chromosomes have a double structure, composed of two structures parallel to each other and joined by a centromere, called chromatids. In each of the "arms" of a chromatid are located genes, in identical position with respect to its counterpart (remember that they are X-shaped), in compartments calledlocus (loci in plural).
As chromosomes are made up of a centromere that divides each chromatid into two arms: a short one (p arm) and a long one (q arm), depending on the location of the centromere, one can speak of:
- Metacentric chromosomes. The centromere is almost in the middle of the structure, forming arms of length very similar.
- Submetacentric chromosomes. The centromere is displaced from the center, but not too much. That forms inaccurate and asymmetrical arms, clearly distinguishable.
- Acrocentric chromosomes. The centromere is at one end, forming largely different arms.
On the other hand, eukaryotic chromosomes have telomeres at their ends: made up of highly repetitive, non-coding DNA regions that fulfill the function of providing structural stability to the entire chromosome.
In prokaryotic organisms (without a cell nucleus), on the other hand, the chromosomes do not have telomeres, since they are circular in shape.
Chromosome function
The function of chromosomes could not be more important: they are responsible for transmitting the genetic information contained in the DNA of the mother cell to the descendants, allowing cell replication and for the growth of organisms, the replacement of old or damaged cells, and the creation of reproductive cells (as well as new individuals during sexual reproduction). These are biological structures that preserve genetic content and prevent (where possible) it from being damaged or lost.
Chromosome types
As has already been seen, there are different chromosomes for eukaryotic cells Y prokaryotes, differentiable in form and function.
- Prokaryotic chromosomes. They have a single DNA strand and are located within the nucleoids scattered throughout the cytoplasm of cells.
- Eukaryotic chromosomes. Considerably larger, they have a double strand of linear DNA (double helix).
However, the chromosomes of the living beings Eukaryotes can also be distinguished according to their specific role in the constitution of the total genome of the individual, something that is extremely important when a new individual of the species is being created through sexual reproduction:
- Somatic chromosomes.Also called autosomal, they give the individual his non-sexual characteristics, that is, those that define him in the rest of the non-reproductive aspects.
- Sex chromosomes. Known as allosomes, they are the chromosomes that determine the sexual characteristics of the individual and therefore can be differentiated according to biological gender: males have a 23 pair of type XY chromosomes, while females have type XX.